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Equipment & Services
The Immunomonitoring Lab provides testing & tissue processing services to its participating members. Below is a list of equipment that is utilized within our core lab along with hyperlinks to additional information on the machine and/or process.
An MHC tetramer assay or simply tetramer assay is a procedure of use labeled tetrameric protein to detect and quantify T-cells that are specific for a given antigen within blood or tissue samples. The IML can produce both MHC class I and class II tetramers for use in both mouse and human systems, which can be adapted for detection by either flow cytometry or CyTOF.
Immune monitoring often entails measuring responses of B and T cells to antigens. The most common method for monitoring lymphocyte responses is the ELISPOT (Enzyme-Linked ImmunoSpot) Assay. The ELISPOT provides a single-cell secretory footprint in the form of a colored spot that is scanned and counted for statistical significance.