Senior Fellows

Ali Ellebedy, PhD

Ali Ellebedy, PhD

Leo Loeb Endowed Professor, Pathology & Immunology

Fellows

Liang Shan, PhD

Liang Shan, PhD

Assistant Professor of Medicine, Division of Infectious Diseases

The Shan lab is broadly interested in host immune response to HIV infection. Novel mouse models that contain multiple human gene knock-ins can improve support human hematopoiesis and maturation and survival of human immune cells in the mouse system. Using the novel humanized mouse models, the Shan lab will study virus-specific human T cell and NK cell responses in controlling HIV-1 infection and clearing viral reservoirs. With the state-of-the-art IML Core Lab at the Bursky Center for Human Immunology, the Shan lab will particularly focus on the antigen-specificity of HIV-specific T cells in order to understand the viral evolution under immune pressure and how to develop vaccine strategies to eradicate HIV infection.